The syndrome presents with pain on the volar aspect of the distal arm and proximal forearm. The symptoms may be aggravated by flexing the elbow against resistance, pronating the forearm against resistance, or flexion of superficialis to the middle finger against resistance, depending on the precise cause of the entrapment.
If the anterior interosseous nerve is also compressed there is weakness of all the muscles innervated by the median nerve, including abductor pollicis brevis and the long finger flexors, and sensory impairment on the palm of the hand.
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